首先就是长期安全性的考验。尽管不少专家认为自免CAR-T的长期风险可能低于肿瘤适应症，FDA的态度也较为积极，但这仍需数年甚至十余年的真实世界数据来最终验证。对于自免患者来说，免疫系统重置后，能否恢复正常功能？如对疫苗的正常应答能力。这需要严谨的上市后研究来回答。
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The use of the word experience, rather than event or presentation, implies that Apple’s typical presentation format won't apply here. And CEO Tim Cook more or less confirmed this when he posted that the company had "a big week ahead," starting on Monday. Apple is most likely planning multiple days of product launches announced via press release on its Newsroom site, with the “experience” on Wednesday serving as a capper and a hands-on session for the media.